evolution of marginal zone lymphoma towards myeloproliferative disorder: a case report
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Evolution of Marginal Zone Lymphoma Towards Myeloproliferative Disorder: A Case Report
Introduction Lymphoma is a hematologic malignancy characterized by nodal or extranodal malignant infiltration by monoclonal lymphoid cells (B lineage cells in 70% of the cases). Its etiology is not precisely known. Prolonged life expectancy has resulted in increase of the disease incidence. Marginal zone lymphoma is a low-grade small B-cell lymphoma incorporated in the World Health Organization...
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Myelofibrosis associated with lymphoid neoplasms is a rare occurrence with the exception of hairy cell leukemia. Its incidence in splenic marginal zone lymphoma, as we report in this article, has only been reported once in the past. We report the case of a 62 year old male with splenic marginal zone lymphoma and concurrent myelofibrosis. The diagnosis of splenic marginal zone lymphoma was achie...
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We present a case of low grade Marginal Zone Lymphoma (MZL) presenting as a dural mass in a 21 year old woman. The patient presented with symptoms of raised intracranial pressure. Imaging findings were suggestive of meningioma. Histological analysis showed proliferation of CD20 positive small lymphoid cells forming nodules that were reminiscent of lymphoid follicles with attenuated germinal cen...
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Nodal follicular lymphoma (FL) is typically composed of follicular or nodular proliferation of small cleaved lymphoid cells, presumably derived from germinal center (GC) B cells. The hallmark of FL is t(14;18)(q32;q21) chromosomal translocation, which juxtaposes anti-apoptotic gene BCL2 to immunoglobulin heavy chain (IGH) promoter. Reflecting this background, FL cells are immunohistochemically ...
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عنوان ژورنال:
iranian journal of blood and cancerجلد ۱، شماره ۴، صفحات ۱۷۱-۱۷۴
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